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HydroTretRx

Hydrating Tretinoin-Powered Treatment

30-day supply • HSA | FSA-eligible

Lock in a healthy glow with HydroTretᴿˣ, designed to be our most hydrating tretinoin formula to keep your skin looking its healthiest.
 

Made with a personalized blend of powerful tretinoin and hydrating dexpanthenol (also known as provitamin B5), this formula helps reinforce your skin barrier to keep essential hydration in while helping to boost collagen production for smoother, healthy-looking skin. 


Beyond hydration benefits, its active ingredients help promote clearer skin by visibly fading dark spots and preventing future breakouts—so you can stay glowing today and tomorrow.

Important safety information

Made to treat:

Fine lines
Wrinkles
Dark spots
Skin texture
One-time purchase
$34.95
Try it with no commitment!
Subscribe and save
$29.95/mo
$5.45
Get your first month FREE—just cover $5.45 shipping and handling!

Ready to target acne or rosacea? Check out Custom FormulaRx

Custom Formula Rx Bottle Top

Ready to target acne or rosacea? Check out Custom FormulaRx

Custom Formula Rx Bottle Top
Dermatologist-tested icon
Dermatologist-tested
Non-comedogenic icon
Non-comedogenic
Paraben-free icon
Paraben-free
Fragrance-free icon
Fragrance-free
Sulfate-free icon
Sulfate-free
Vegan icon
Vegan
Cruelty-free icon
Cruelty-free
Prescription skincare made personal
Curology Provider holding Custom Formula Rx bottle

Jennifer Kolinski, NP-C

Pr

Curology provider

A trusted expert who designs a treatment plan for your unique skin and goals

We can prescribe 3 custom-strength ingredients in 1 formula for your skin.

TrTretinoin
tretinoin@2x
  • Fine lines

“Tretinoin is well-known for reducing fine lines, evening out skin tone, and enhancing the skin's overall appearance.”

-Nancy Satur, MD

“Tretinoin is well-known for reducing fine lines, evening out skin tone, and enhancing the skin's overall appearance.”

-Nancy Satur, MD

AzAzelaic acid
azelaicAcid@2x
  • Dark spots

“Azelaic acid is a gentle exfoliant that can help patients achieve a smoother skin texture.”

-Nancy Satur, MD

“Azelaic acid is a gentle exfoliant that can help patients achieve a smoother skin texture.”

-Nancy Satur, MD

DeDexpanthenol
Dexpanthenol
  • Hydration

“I love dexpanthenol because it helps with wound healing and also helps soothe skin irritation."

-Nancy Satur, MD

“I love dexpanthenol because it helps with wound healing and also helps soothe skin irritation."

-Nancy Satur, MD

0.02%
5%
1%
HydroTret Rx Bottle

Check out all potential active ingredients

Ingredients subject to consultation.

HydroTret Rx Bottle

Help hydrate while you fight early signs of aging*

Mu - Before
Before
Mu - After
After 6 months
Mu - Before
Before
Mu - After
After 6 months
Results may vary

Mu

I am satisfied with my journey.

Vivian - Before
Before
Vivian - After
After 1 year
Vivian - Before
Before
Vivian - After
After 1 year
Results may vary

Vivian

It changed my skin.

Courtney - Before
Before
Courtney - After
After 1 year
Courtney - Before
Before
Courtney - After
After 1 year
Results may vary

Courtney

My skin is nearly perfect thanks to Curology!

Trevor - Before
Before
Trevor - After
After 2 years
Trevor - Before
Before
Trevor - After
After 2 years
Results may vary

Trevor

My skin has gotten much clearer and smoother.

Melissa - Before
Before
Melissa - After
After 4 years
Melissa - Before
Before
Melissa - After
After 4 years
Results may vary

Melissa

I saw results in the first 2 weeks and was hooked from there. Not sure I’ll ever be without my Curology products.

Annie - Before
Before
Annie - After
After 2 years
Annie - Before
Before
Annie - After
After 2 years
Results may vary

Annie

It helps with my acne, and it helps with the dryness that tretinoin typically causes.

Marian - Before
Before
Marian - After
After 1 year
Marian - Before
Before
Marian - After
After 1 year
Results may vary

Marian

It has improved my skin drastically and helped get rid of the painful cysts I used to get.

Emily - Before
Before
Emily - Before
After 8 months
Emily - Before
Before
Emily - After
After 8 months
Results may vary

Emily

Things are starting to clear up!

Audra - Before
Before
Audra - After
After 1 year
Audra - Before
Before
Audra - After
After 1 year
Results may vary

Audra

[I] switched to the HydroTretᴿˣ, and now that has been working great for me!

Sheri - Before
Before
Sheri - After
After 1 year
Sheri - Before
Before
Sheri - After
After 1 year
Results may vary

Sheri

My skin became smoother with a noticeable glow that made my skin look less tired.

*Results may vary. Product and ingredients subject to medical consultation. Subscription required. Restrictions apply.

Designed to be our most hydrating tretinoin formula*

Renew and hydrate with HydroTretᴿˣ.

*Results may vary. Product and ingredients subject to medical consultation. Subscription required. Restrictions apply.
256 Curology Hydro Launch Application Hydrotret 1418 (1)

How it works

  1. acneDesktop@1x.jpg
    1

    Tell us about you

    Begin your consultation by answering quick questions about your skin, goals, and medical history—plus sharing photos.

    Begin your consultation by answering quick questions about your skin, goals, and medical history—plus sharing photos.

    acneMobile@1x.jpg
  2. HowitWorks Step2 Mobile
    2

    Connect with your provider

    Get matched with a dermatology provider who reviews your info and photos to prescribe a personalized formula for your skin.

    Get matched with a dermatology provider who reviews your info and photos to prescribe a personalized formula for your skin.

    How it works Step 2 Mobile
  3. Future proof bottle
    3

    Start your routine

    Follow your prescribed treatment plan and see how your skin transforms. Plus, shop non-Rx products for your new routine anytime.

    Follow your prescribed treatment plan and see how your skin transforms. Plus, shop non-Rx products for your new routine anytime.

    Future proof bottle
  4. Pre-DP how it works tile 4
    4

    Get ongoing support

    Message your provider anytime with your skin questions. They can adjust your ingredients or prescribe a new Rx formula as your goals change.

    Message your provider anytime with your skin questions. They can adjust your ingredients or prescribe a new Rx formula as your goals change.

    Pre-DP how it works tile 4
Subject to medical consultation.

FAQs

What ingredients are in HydroTretᴿˣ?

A licensed dermatology provider selects 3 active ingredients at the right strength for your skin.

Potential active ingredients include:

  • Tretinoin

  • Dexpanthenol (aka provitamin B5)

  • Niacinamide

  • Azelaic acid

Inactive ingredients: Aloe Barbadensis Leaf Juice, C13-14 Isoparaffin, Caprylic/Capric Triglyceride, Deionized Water, Laureth-7, Phenoxyethanol, Polyacrylamide, Tocopheryl Acetate, Triethylene Glycol. 

All formulas containing tretinoin also contain the antioxidant butylated hydroxytoluene (BHT), and formulas containing both niacinamide and azelaic acid may also contain propylene glycol. All formulas containing dexpanthenol also contain propylene glycol.

How do you use HydroTretᴿˣ?

Our licensed dermatology providers generally advise that after cleansing with Hydro+ Foaming Gel Cleanser, apply a thin layer of HydroTretᴿˣ to your entire face and neck before bed. Leave on overnight. As always, follow your provider’s instructions for your unique skin.

Who is HydroTretᴿˣ for?

HydroTretᴿˣ is designed for dry, sensitive skin. It may be suitable if you want to add tretinoin into your routine but haven’t been able due to concerns around dryness and irritation. Curology also offers a tretinoin-free HydroTretᴿˣ if that is a better option for your unique skin.

Is HydroTretᴿˣ suitable for all skin types?

Yes, HydroTretᴿˣ can be used by all skin types (dry, combination, oily, and sensitive). Check with your Curology dermatology provider to see if HydroTretᴿˣ is a good option for your skin.

How is HydroTretᴿˣ personalized?

Your Curology dermatology provider can prescribe you a formula containing up to 3 active ingredients, based on your skin quiz, photos, and consultation. Your formula will target your specific skin concerns and can evolve with you over time!

Can you use your HSA or FSA for Curology?

You may be able to use your HSA or FSA pre-tax dollars for this Curology product, plus some of our other acne treatments and sunscreens. Check with your plan’s administrator to confirm eligibility. Restrictions apply.

After your 30-day free trial, you can update your payment method to your HSA or FSA card via your account dashboard. Or you can use a credit or debit card and submit a claim for reimbursement—just download your itemized receipt for your order from your account dashboard.

Learn more

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