Skip to main content

How it works:

  • Share your skin goals and snap selfies

  • Your dermatology provider prescribes your formula

  • Apply nightly for happy, healthy skin

How it works:

  • Share your skin goals and snap selfies

  • Your dermatology provider prescribes your formula

  • Apply nightly for happy, healthy skin

  1. blog
  2. > Ask Dr. Whitney

Why is DayPrimeᴿˣ different? Ask Dr. Whitney

The first-ever prescription acne treatment and blurring primer is unlike any product you’ve tried before. Board-certified dermatologist and Curology’s Medical Director, Dr. Whitney Tolpinrud, MD, FAAD, breaks down the benefits that set DayPrimeRx apart.

Curology Team Avatar
by Curology Team
Updated on Oct 17, 2025 • 3 min read
Medically reviewed by Dr. Whitney Tolpinrud
dp 101 thumb
Curology Team Avatar
by Curology Team
Updated on Oct 17, 2025 • 3 min read
Medically reviewed by Dr. Whitney Tolpinrud
We’re here to share what we know — but don’t take it as medical advice. Talk to your medical provider if you have questions.

Summary

Learn more about Curology’s new prescription acne treatment and blurring primer in one. It is designed for daytime use with a primer base for soft-focus, smoother-looking skin, while personalized Rx active ingredients target your skin concerns for healthier-looking skin over time.

whitney DP

Watch this video to learn the about DayPrimeᴿˣ from Dr. Whitney

How does DayPrimeᴿˣ work?

This 2-in-1 acne treatment and primer is made using a personalized blend of active ingredients prescribed by a licensed dermatology provider. DayPrimeᴿˣ works immediately to visibly blur imperfections, minimize the look of pores, and even out texture, while the personalized prescription ingredients work over time to target acne, dark spots, rosacea, and clogged pores for healthier looking skin over time. The active ingredients in your formula will be prescribed for your unique skin goals and may include: Azelaic Acid, Clindamycin, Dexpanthenol, Niacinamide, Salicylic Acid, or Zinc Pyrithione.

dprx ingredients

How does DayPrimeᴿˣ fit in my skincare routine?

DayPrimeᴿˣ fits seamlessly into your routine, after cleansing and moisturizing, to enhance the appearance of your skin and target your goals all day. Apply it after cleansing in the AM, and let dry fully before adding sunscreen or makeup. Use DayPrimeᴿˣ on its own in the morning or pair it with Custom Formulaᴿˣ or HydroTretᴿˣ at night for for around-the-clock treatment. 

dprx routine

DayPrimeᴿˣ application tips:

  • Apply a thin layer of DayPrimeᴿˣ after cleansing and moisturizing.

  • Gently pat (don’t rub!) into your skin— avoid heavy layers.

  • Allow DayPrimeᴿˣ to dry fully before applying your next layer. This helps it sit better and reduces the chance of pilling, creating an ideal canvas for makeup.

  • Pair with silicone-based foundation for best results.

dprx lifestyle

Questions or concerns?


Since this is a prescription product, always follow your licensed dermatology provider’s instructions for how to best use it with your unique skin.

dprx medical

Ready to start DayPrimeᴿˣ? Try it for free* for 30 days and get your personalized prescription treatment.



Just pay $5.45 in shipping and handling. Subscription required.


*Subject to medical consultation. Applies only to your first box. Trial lasts 30 days. New subscribers only. Restrictions apply. See website for full details and important safety information.

Curology Team Avatar

Curology Team

whitney avatar

Dr. Whitney Tolpinrud

Related Articles

Meet Dr. Whitney Tolpinrud, MD, FAAD—Medical Director at CurologyAsk Dr. Whitney: What are post-acne marks and how can I treat them?Ask Dr. Whitney: How do I treat acne?Ask Dr. Whitney: What causes acne?

Popular Articles

Ask Curology: Is my cold breaking me out?Slugging: The dermatologist-approved skincare hack going viral on TikTokTretinoin vs retinol: What’s the difference?How to create a self-care routine that actually sticksYour 2023 skincare horoscope
Try prescription skincare
30-day trial. Subject to consultation. Cancel anytime.
Get routine essentials
Get StartedShop ProductsWhy CurologyGuidesOur StoryCommunity
All Rights Reserved 2014-2025 Curology Inc.
Terms of ServicePrivacy Notice
Do Not Sell or Share My Personal Information